1. From the National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences (H.-L.L., Z.-G.S., A.-B.W., Y.-S.W., D.-P.L.) and Institute of Medicinal Biotechnology (T.-B.L., Y.-G.W.), Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China; Joslin Diabetes Center and Department of Medicine (H.-L.L.), Harvard Medical School, Boston, Mass; and the Cardiovascular Research Institute (Q.Y.), Morehouse School of Medicine, Atlanta, Ga.