1. From the Drug Discovery Biology (Y.B., A.K., B.R., R.S., N.K., A.K.S., M.S., D.S.S., H.F., W.F., O.N.) and Drug Discovery Pharmacology and Preclinical Development (P.H., C.Q., D.W., K.K., M.C.), Actelion Pharmaceuticals Ltd, Allschwil, Switzerland.