1. From the Department of Internal Medicine and the Institute for Cardiovascular Research-Vrije Universiteit (M.P.B., R.G.IJ., R.T.J., E.C.E., Y.M.S., E.H.S., C.D.A.S.), VU University Medical Center Amsterdam, The Netherlands; and the Department of Internal Medicine and the Cardiovascular Research Institute Maastricht (C.D.A.S.), University Hospital Maastricht, The Netherlands.