1. From the British Heart Foundation Glasgow Cardiovascular Research Centre (D.G., N.N.H., C.A.H., E.B., A.F.D.), Faculty of Medicine, University of Glasgow, Glasgow, United Kingdom; Department of Chemistry (R.A.J.S.), University of Otago, Dunedin, New Zealand; Medical Research Council Mitochondrial Biology Unit (H.M.C., M.P.M.), Cambridge, United Kingdom.