1. From the Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland (A.V.S.), Dublin, Ireland; Division of Cardiovascular Diseases, Western Pennsylvania Hospital (A.H.G.), Pittsburgh, Pa; Department of Nephrology and Hypertension, University of Erlangen-Nürnberg (R.E.S.), Erlangen, Germany; Department of Medicine, Centre Hospitalier Universitaire Vaudois (J.N.), Lausanne, Switzerland; Novartis Pharmaceuticals Corporation (R.S., M.F.P.), East Hanover, N.J.