Bradykinin Stimulates Renal Na+and K+Excretion by Inhibiting the K+Channel (Kir4.1) in the Distal Convoluted Tubule

Author:

Zhang Dan-Dan1,Gao Zhong-Xiuzi2,Vio Carlos P.3,Xiao Yu1,Wu Peng2,Zhang Hao1,Guo Xi-Wen1,Meng Xin-Xin1,Gu Li1,Wang Jun-Lin1,Duan Xin-Peng1,Lin Dao-Hong2,Wang Wen-Hui2,Gu Ruimin1

Affiliation:

1. From the Department of Physiology, Harbin Medical University, China (D.-D.Z., Y.X., H.Z., X.-W.G., X.-X.M., L.G., J.-L.W., X.-P.D., R.G.)

2. Department of Pharmacology, New York Medical College, Valhalla (Z.-X.G., P.W., D.-H.L., W.-H.W.)

3. Department of Physiology, Center for Aging and Regeneration Care-UC, Pontificia Universidad Catolica de Chile, Santiago (C.P.V.).

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Internal Medicine

Reference40 articles.

1. The kallikrein-kinin system as a regulator of cardiovascular and renal function.;Rhaleb NE;Compr Physiol,2011

2. Evidence for a stimulatory effect of high potassium diet on renal kallikrein

3. Potassium supplement upregulates the expression of renal kallikrein and bradykinin B2 receptor in SHR.;Jin L;Am J Physiol,1999

4. Involvement of the renal kallikrein–kinin system in K+-induced diuresis and natriuresis in anesthetized rats

5. Enhanced renal function in bradykinin B2 receptor transgenic mice

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