1. From the Departments of Pharmacology (H.A.J.S.-B., B.F.J.H.) and Epidemiology (J.A.S.), Maastricht University, Maastricht, the Netherlands; Division of Hypertension and Cardiac Rehabilitation Department of Cardiovascular Sciences (Y.-P.L., J.A.S.), University of Leuven, Leuven, Belgium.