1. From the Institute of Experimental and Clinical Pharmacology and Toxicology and BIOSS Centre for Biological Signalling Studies (A.L., R.G., S.R., A.E., F.B., L.H.), University of Freiburg, Freiburg, Germany; German Cancer Research Center (S.B., G.S.), Heidelberg, Germany; Klinik für Kardiologie und Angiologie (J.B.), Medizinische Hochschule Hannover, Hannover, Germany.