1. From the Hypertension and Vascular Research Center and Physiology and Pharmacology Department (A.C.A., C.M.F., D.I.D.), Wake Forest University School of Medicine, Winston-Salem, NC; and the Cardiovascular Medicine (A.S.), Nephrology and Neurology, University of the Ryukyus School of Medicine, Okinawa, Japan; Charite—Universitatsmedizin (D.G.), Berlin, Germany.