Influence of Gallogen and Diethanolamine Upon Induced Hypercholesterolemia in the Rat

Author:

DAYTON SEYMOUR1

Affiliation:

1. Department of Medicine, University of California School of Medicine, Los Angeles, Calif

Abstract

The diethanolamine salt of the mono (α,p-dimethylbenzyl) ester of d-camphoric acid (Gallogen) augmented diet-induced hypercholesterolemia and hyperlipemia in the rat, while depressing liver cholesterol and total lipid concentrations. Diethanolamine had virtually identical effects. Gallogen, given orally to rats with biliary fistulas had a slight hydrocholeretic effect, but did not influence biliary excretion of cholesterol, cholic acid, or chenodeoxycholic acid.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Synthesis, reactions, applications, and biological activity of diethanolamine and its derivatives;Russian Journal of Organic Chemistry;2013-07

2. Drugs Acting on Lipid Catabolism and Excretion;Medicinal Chemistry;1964

3. Biological Activity of the Terpenoids and Their Derivatives;Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques;1963

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