Affiliation:
1. From the Department of Medicine (Cardiac Unit), Massachusetts General Hospital, Harvard Medical School, Boston, Mass.
Abstract
Background
This study is the clinical follow-up (20±12 months; range, 6 to 49 months) of 327 patients who had percutaneous mitral balloon valvotomy (PMV) at the Massachusetts General Hospital.
Methods and Results
There were seven in-hospital deaths. Patients were divided into two groups according to their echocardiographic score; 211 patients had echocardiographic scores ≤8 and 116, echocardiographic scores >8. Patients with echocardiographic scores >8 were older (64±11 versus 48±14 years,
P
<.01), and more had atrial fibrillation (65% versus 40%,
P
<.01), calcium under fluoroscopy (81% versus 29%,
P
<.01), and previous surgical commissurotomy (30% versus 16%,
P
<.01) than patients with echocardiographic scores ≤8. With PMV, mitral valve area increased from 1.0±0.3 to 2.2±0.8 cm
2
in patients with echocardiographic scores ≤8 and from 0.8±1 to 1.7±0.7 cm
2
in those with echocardiographic scores >8. Rates of survival (98±2% versus 72±11%), survival with freedom from mitral valve replacement (91±4% versus 55±13%), and survival with freedom from combined events (79±10% versus 39±18%) at follow-up were greater in patients with echocardiographic scores ≤8 (
P
<.00005). Cox regression analysis identified the echocardiographic score as the most important unfavorable intermediate long-term follow-up prediction factor after PMV.
Conclusions
The excellent intermediate long-term clinical follow-up of patients with echocardiographic score ≤8 and no calcified mitral valves suggests that PMV may be the treatment of choice in this group of patients.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine
Cited by
127 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献