Affiliation:
1. the Royal Brompton Hospital, National Heart and Lung Institute, Imperial College, London, UK.
Abstract
Background
We have previously shown that QRS prolongation (≥180 ms) is a risk marker for sustained ventricular tachycardia (VT) late after repair of tetralogy of Fallot (rTOF). We have now examined the dispersion of QT and its components QRS and JT, in an attempt to determine whether any association exists between these measurements and the presence of VT in these patients.
Methods and Results
QRS duration and QT/QRS/JT dispersion were measured manually from standard ECGs in 10 syncopal rTOF patients (21.4±4.6 years after repair; group 1) with QRS≥180 ms and with documented VT and were compared with 9 rTOF patients with QRS ≥180 ms and no VT (group 2), 40 rTOF patients with QRS <180 ms and no clinical arrhythmias (group 3), and 40 nontetralogy control subjects (20 with right bundle-branch block [group 4] and 20 with normal ECG patterns [group 5]). Mean QT dispersion (62±36 ms) in the tetralogy patients was greater than in the nontetralogy control subjects (34±10 ms,
P
<.001). There were significant differences in all measured parameters between groups 1 and 3 and more importantly between groups 1 and 2. QRS dispersion in group 1 also correlated with QRS duration but not with JT dispersion.
Conclusions
Our data suggest that both depolarization and repolarization abnormalities are associated with VT after rTOF. Furthermore, increased QT, QRS, and JT dispersions, combined with a QRS≥180 ms, refine risk stratification for VT in these patients.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine
Reference26 articles.
1. Long-Term Outcome in Patients Undergoing Surgical Repair of Tetralogy of Fallot
2. Rosing DR Borer JS Kent KM Maron BJ Seides SF Morrow AG Epstein SE. Long-term hemodynamic and electrocardiographic assessment following operative repair of tetralogy of Fallot. Circulation . 1978;58(suppl I):I-209-I-217.
3. QT dispersion: an indication of arrhythmia risk in patients with long QT intervals.
Cited by
114 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献