1. From the Department of Medical Biochemistry and Molecular Biology (O.R., I.K., E.V., R.P.), Research Centre of Applied and Preventive Cardiovascular Medicine (O.R), and Department of Surgery (H.H.), University of Turku, Finland, the CIHR Group in Matrix Dynamics (M.S), University of Toronto, Canada, and the Departments of Biochemistry and Medicine (S.H., P.B.), University of Washington, Seattle, Wash. Present address for S.G.H. is University Hospital of Neurology, Heidelberg, Germany.