Critical Role of Macrophage 12/15-Lipoxygenase for Atherosclerosis in Apolipoprotein E

Critical Role of Macrophage 12/15-Lipoxygenase for Atherosclerosis in Apolipoprotein E–Deficient Mice

Published:2004-10-05 Issue:14 Volume:110 Page:2024-2031
ISSN:0009-7322
Container-title:Circulation
language:en
Short-container-title:Circulation

Author:

Huo Yuqing¹,Zhao Lei¹,Hyman Matthew Craig¹,Shashkin Pavel¹,Harry Brian L.¹,Burcin Tracy¹,Forlow S. Bradley¹,Stark Matthew A.¹,Smith David F.¹,Clarke Sean¹,Srinivasan Suseela¹,Hedrick Catherine C.¹,Praticò Domenico¹,Witztum Joseph L.¹,Nadler Jerry L.¹,Funk Colin D.¹,Ley Klaus¹

Affiliation:

1. From the University of Virginia (Y.H., M.C.H., P.S., B.L.H., T.B., S.B.F., M.A.S., D.F.S., S.C., S.S., C.C.H., J.L.N., K.L.), Charlottesville, Va; University of Pennsylvania (L.Z., D.P., C.D.F.), Philadelphia, Pa; and University of California (J.L.W), San Diego, Calif.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference34 articles.

1. Atherosclerosis — An Inflammatory Disease

2. Mammalian lipoxygenases: molecular structures and functions

3. The molecular biology of mammalian lipoxygenases and the quest for eicosanoid functions using lipoxygenase-deficient mice

4. Oxidative modification of human lipoproteins by lipoxygenases of different positional specificities

5. The Rabbit 15-Lipoxygenase Preferentially Oxygenates LDL Cholesterol Esters, and This Reaction Does Not Require Vitamin E

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