1. From the Vascular Biology Group (B.T., E.D.M., X.-C.W., R.M., J.R.B.D., G.H., K.H., A.H., S.L.A.), Department of Physiology (S.L.A.), Department of Pediatrics (B.T., J.R.B.D.), Cardiovascular Research Group and Department of Pharmacology (J.R.B.D.), and Division of Cardiovascular Surgery (I.R.), University of Alberta, Edmonton, Alberta, Canada; and Ciphergen Biosystems Inc (M.K.), Freemont, Calif.