1. From the Department of Medicine (Vascular Medicine, Cardiology, Cardiovascular Research), St Elizabeth’s Medical Center, Tufts University School of Medicine (S.M., J.L., M.S., J.M.I., D.W.L., T.A.), Boston, Mass; Stem Cell Translational Research, Kobe Institute of Biomedical Research and Innovation/Riken Center for Developmental Biology (S.M., T.A.), Kobe, Japan; Department of Physiology, Tokai University School of Medicine (T.A.), Kanagawa, Japan.