1. From the I.R.C.C.S. Neuromed (C.V., L.F., A.N., R.P., G.F., V.T., B.T., G.L.), Pozzilli (IS), Italy; Internal Medicine Department of Medical and Surgical Sciences (D.R., E.P., D.G., E.A.-R.), University of Brescia, Italy; Department of Pharmacology (M.J.M.), University of Aarhus, Aarhus, Denmark; Institut de Pharmacologie et Toxicologie (S.C.), Université de Lausanne, Switzerland; and Department of Experimental Medicine and Pathology (G.L.), La Sapienza University of Rome, Italy.