The potentiation of warfarin anticoagulation by amiodarone.-Reference-Cited by-同舟云学术

The potentiation of warfarin anticoagulation by amiodarone.

Published:1982-05 Issue:5 Volume:65 Page:1025-1029
ISSN:0009-7322
Container-title:Circulation
language:en
Short-container-title:Circulation

Author:

Hamer A,Peter T,Mandel W J,Scheinman M M,Weiss D

Abstract

The potentiation of the anticoagulant effect of sodium warfarin by amiodarone is reported in 10 patients. Amiodarone appears to augment the depression of vitamin K-dependent coagulation factors caused by warfarin by an uncertain mechanism, and may lead to serious bleeding. The maintenance dose of warfarin should be halved when amiodarone and warfarin are prescribed together.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Link

https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.65.5.1025

Reference9 articles.

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4. Effect of amiodarone in the Wolff-Parkinson-White syndrome

5. Use of amiodarone in bradycardia-tachycardia syndrome.

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