Some Determinants of Coronary Collateral Blood Flow in the Open-Chest Dog-Reference-Cited by-同舟云学术

Some Determinants of Coronary Collateral Blood Flow in the Open-Chest Dog

Published:1959-07 Issue:4 Volume:7 Page:628-642
ISSN:0009-7330
Container-title:Circulation Research
language:en
Short-container-title:Circulation Research

Author:

KATTUS A. A.¹,GREGG D. E.¹

Affiliation:

1. Department of Cardiorespiratory Diseases, Walter Reed Army Institute of Research, Walter Reed Army Medical Center, Washington, D. C.

Abstract

Dynamics of the coronary collateral circulation have been investigated by means of the retrograde flow technic. A principal determinant of retrograde flow appears to be the perfusion pressure irrespective of the rate of coronary inflow. Nitroglycerine, histamine and norepinephrine failed to augment retrograde flow. Reactive hyperemia and temporary myocardial ischemia resulted in a reduction of retrograde flow which could be due to active vasoconstriction or to myocardial stretching. Changes in heart rate and the onset of ventricular fibrillation did not alter retrograde flow, but low blood viscosity increased it.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Link

https://www.ahajournals.org/doi/pdf/10.1161/01.RES.7.4.628

Reference13 articles.

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4. The magnitude, adequacy, and source of the collateral blood flow and pressure in chronically occluded coronary arteries;GREGG D. E.;Am. J. Physiol.,1939

5. The magnitude and time of development of the collateral circulation in occluded femoral, carotid, and coronary arteries;ECKSTEIN R. W.;Am. J. Physiol.,1941

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