Effect of Potassium and "Toxic" Doses of Digitalis on the Myocardium-Reference-Cited by-同舟云学术

Effect of Potassium and "Toxic" Doses of Digitalis on the Myocardium

Published:1959-05 Issue:3 Volume:7 Page:424-431
ISSN:0009-7330
Container-title:Circulation Research
language:en
Short-container-title:Circulation Research

Author:

FISCH CHARLES¹,STEINMETZ EDWARD F.¹,FASOLA ALFRED F.¹,MARTZ B. L.¹

Affiliation:

1. Robert M. Moore Heart Clinic and Lilly Laboratory for Clinical Research, Indianapolis General Hospital, and the Department of Medicine, Indiana University School of Medicine

Abstract

This study was designed to evaluate further the antagonism between digitalis and potassium. Potassium was given by intravenous infusion to six dogs (1) before digitalization, (2) after injection of "therapeutic" doses of digitoxin, and finally (3) after injection of "toxic" doses of the drug.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Link

https://www.ahajournals.org/doi/pdf/10.1161/01.RES.7.3.424

Reference19 articles.

1. The Therapeutic Use of Potassium in Certain Cardiac Arrhythmias.

2. THE TREATMENT OF CERTAIN CARDIAC ARRHYTHMIAS WITH POTASSIUM SALTS

3. The effect on man of potassium administration in relation to digitalis glycosides, with special reference to blood serum potassium, the electrocardiogram, and ectopic beats

4. Current Concepts in Digitalis Therapy

5. The effect of intravenous administration of potassium chloride on ectopic rhythms, ectopic beats and disturbances in A-V conduction

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1. Factors affecting tolerance to digitalis;Journal of the American College of Cardiology;1985-05

2. Effects of hyperkalemia on the electrocardiogram of patients receiving digitalis;The American Journal of Cardiology;1985-04

3. Combined Effects of Ouabain and Hypoxia on the Transmembrane Potential of Canine Cardiac Purkinje Fibers;Journal of Cardiovascular Pharmacology;1985-03

4. Antiarrhythmic agents and their use in therapy;Pharmacology & Therapeutics;1980-01

5. Antiarrhythmic Agents;Clinical Applications of Cardiovascular Drugs;1980