DASH Score and Subsequent Risk of Coronary Artery Disease: The Findings From Million Veteran Program
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Published:2018-05
Issue:9
Volume:7
Page:
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ISSN:2047-9980
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Container-title:Journal of the American Heart Association
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language:en
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Short-container-title:JAHA
Author:
Djoussé Luc12, Ho Yuk‐Lam1, Nguyen Xuan‐Mai T.12, Gagnon David R.13, Wilson Peter W.F.4, Cho Kelly12, Gaziano J. Michael12, Halasz Ildiko, Federman Daniel, Beckham Jean, Sherman Scott E., Sriram Peruvemba, Tsao Philip S., Boyko Edward J., Xu Junzhe, Lederle Frank, Dellitalia Louis J., McArdle Rachel, Kaminsky Laurence, Swann Alan C., Hamner Mark B., Florez Hermes J., Pandya Prashant, Villarreal Gerardo, Wilson Peter, Morgan Timothy R., Davis Lori, Hurley Robin A., Meyer Laurence, Ahuja Sunil K., Konicki Eric P., Cohen David, Lichy Jack, Whittle Jeffrey, Haddock Kathlyn Sue, Straub Karl D., Callaghan John T., Aguayo Samuel M., Gupta Samir, Washburn Ronald G., Oehlert Mary E., Hung Adriana M., Wallbom Agnes, Keith Robert, Sonel Elif, Schifman Ronald B., Childress Richard D., Godschalk Michael F., Shuldiner Alan R., Rastogi Padmashri, Gutierrez Salvador, Fernando Ronald, Iruvanti Pran R., Jhala Darshana, Rosado‐Rodriguez Carlos, Mastorides Stephen M., Harley John B., Mattocks Kristin, Striker Robert T., Rauchman Michael, Wells John, Ballas Zuhair K., Woods Susan S., Yeh Shing, Ratcliffe Nora R., Klein Jon B., Golden Adam G., Ginzburg Harold M., Sharma Satish, Oursler Kris Ann K., Whooley Mary A., Gibson Gretchen,
Affiliation:
1. Massachussets Veterans Epidemiology Research and Information Center, Boston VA Healthcare System, Boston, MA 2. Harvard Medical School, Boston, MA 3. Boston University School of Public Health, Boston, MA 4. Atlanta VA Healthcare System and Emory School of Medicine, Atlanta, GA
Abstract
Background
While adherence to healthful dietary patterns has been associated with a lower risk of coronary artery disease (CAD) in the general population, limited data are available among US veterans. We tested the hypothesis that adherence to Dietary Approach to Stop Hypertension (DASH) food pattern is associated with a lower risk of developing CAD among veterans.
Methods and Results
We analyzed data on 153 802 participants of the Million Veteran Program enrolled between 2011 and 2016. Information on dietary habits was obtained using a food frequency questionnaire at enrollment. We used electronic health records to assess the development of CAD during follow‐up. Of the 153 802 veterans who provided information on diet and were free of CAD at baseline, the mean age was 64.0 (SD=11.8) years and 90.4% were men. During a mean follow‐up of 2.8 years, 5451 CAD cases occurred. The crude incidence rate of CAD was 14.0, 13.1, 12.6, 12.3, and 11.1 cases per 1000 person‐years across consecutive quintiles of Dietary Approach to Stop Hypertension score. Hazard ratios (95% confidence interval) for CAD were 1.0 (ref), 0.91 (0.84–0.99), 0.87 (0.80–0.95), 0.86 (0.79–0.94), and 0.80 (0.73–0.87) from the lowest to highest quintile of Dietary Approach to Stop Hypertension score controlling for age, sex, body mass index, race, smoking, exercise, alcohol intake, and statin use (
P
linear trend, <0.0001).
Conclusions
Our data are consistent with an inverse association between Dietary Approach to Stop Hypertension diet score and incidence of CAD among US veterans.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Cardiology and Cardiovascular Medicine
Cited by
33 articles.
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