1. From the Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Multimedica (D.C., G.C.), Milan, Italy; Department of Cardiovascular Medicine and Fondazione San Raffaele (P.G.), Campus BioMedico University, Rome, Italy; and Division of Cardiology (G.C.), Department of Medicine, University of California San Diego, La Jolla, Calif.