1. From the Department of Molecular Genetics, Biocenter and University of Vienna, Austria (S.M., H.B., J.N., W.J.S.); the Second Department of Internal Medicine, Chiba University School of Medicine, Japan (H.Y., H.B., J.K., T.K., K.S., N.M., Y.S.); and the Department of Cell Biology, Kowa Research Institute, Kowa Co Ltd, Tsukuba, Japan (H.Y.).