Author:
Holme I,Enger S C,Helgeland A,Hjermann I,Leren P,Lund-Larsen P G,Solberg L A,Strong J P
Abstract
In 1972-1973, about 16,200 men living in Oslo, aged 40 to 49 years, were examined for cardiovascular disease, and had a number of coronary risk factors measured. This report gives the results of 129 autopsied cases with regard to the association between raised atherosclerotic lesions in coronary and cerebral arteries and various coronary risk factors. For coronary raised lesions, the high density lipoprotein (HDL) cholesterol ratio was the most significant risk factor. Systolic blood pressure and total serum cholesterol were also significantly associated. Physical activity at work and at leisure, nonfasting triglycerides, and cigarette smoking did not show a significant association with coronary artery raised lesions. The association between total serum cholesterol and systolic blood indicates that total serum cholesterol may be more important than systolic pressure in the synergism affecting the development of coronary atherosclerosis. For cerebral artery raised lesions, blood pressure was the most important risk factor, even though serum cholesterol was highly associated with the lesions. The interaction analysis also suggested that blood pressure was more important than serum cholesterol in the synergism.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Cardiology and Cardiovascular Medicine
Reference22 articles.
1. Strong JP Eggen DA Tracy RE. The geographic pathology and topography of atherosclerosis and risk factors for atherosclerotic lesions. In: Chandler AB Eurenius K McMillan GC Nelson CB Schwartz CJ Wessler S eds. The thrombotic process in atherogenesis. New York: Plenum Press 1978: 11-31
2. Risk factors for coronary and cerebral atherosclerosis in the Oslo Study. In: Gotto JM Jr, Smith LC, Allen B, eds;Solberg LA;Atherosclerosis V. New York: Springer-Verlag,1980
3. Atherosclerosis, smoking and other risk factors. In: Gotto JM Jr, Smith LC, Allen B, eds;Sternby NH;Atherosclerosis V. New York: Springer-Verlag,1980
4. The relation of antemortem factors to atherosclerosis at necropsy. In: Schettler GY, Goto Y, Hata Y, Klose G, eds. Atherosclerosis IV;Garcla-Palmlerl MR;New York: Springer-Verlag,1977
5. Atherosclerosis and its risk factors among Hawaii Japanese. In: Gotto JM Jr, Smith LC, Allen B, eds;Stemmermann GN;Atherosclerosis V. New York: Springer-Verlag,1980
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