Characterization of SEMA3A -Encoded Semaphorin as a Naturally Occurring K v 4.3 Protein Inhibitor and its Contribution to Brugada Syndrome

Author:

Boczek Nicole J.1,Ye Dan1,Johnson Eric K.1,Wang Wei1,Crotti Lia1,Tester David J.1,Dagradi Federica1,Mizusawa Yuka1,Torchio Margherita1,Alders Marielle1,Giudicessi John R.1,Wilde Arthur A.M.1,Schwartz Peter J.1,Nerbonne Jeanne M.1,Ackerman Michael J.1

Affiliation:

1. From the Center for Clinical and Translational Science (N.J.B.) and Mayo Graduate School (N.J.B.), Department Molecular Pharmacology and Experimental Therapeutics, Windland Smith Rice Sudden Death Genomics Laboratory (D.Y., D.J.T., J.R.G., M.J.A.), Department of Medicine (J.R.G.), Division of Cardiovascular Diseases (M.J.A.), and Division of Pediatric Cardiology (M.J.A.), Mayo Clinic, Rochester, MN; Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St Louis,...

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Reference28 articles.

1. The function of semaphorins during nervous system development

2. Abstract 1243: Sema3a induces a cardiac ventricular repolarization gradient via sympathetic innervation patterning.;Ieda M;Circulation,2006

3. Sema3a maintains normal heart rhythm through sympathetic innervation patterning

4. New Perspectives on the Role of Autonomic Nervous System in the Genesis of Arrhythmias

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