Some Effects of Digoxin on the Heart and Circulation in Man-Reference-Cited by-同舟云学术

Some Effects of Digoxin on the Heart and Circulation in Man

Published:1951-09 Issue:3 Volume:4 Page:366-377
ISSN:0009-7322
Container-title:Circulation
language:en
Short-container-title:Circulation

Author:

HARVEY RÉJANE M.¹,FERRER M. IRENÉ¹,CATHCART RICHARD T.¹,ALEXANDER JAMES K.¹

Affiliation:

1. From the Department of Medicine, Columbia University College of Physicians and Surgeons, and the Cardiopulmonary Laboratory of the First Medical and Chest Services (Columbia University Division), Bellevue Hospital, New York, N. Y.

Abstract

The early effect of intravenous Digoxin was observed in 12 patients with cardiac enlargement in whom there was no clinical or physiologic evidence of failure. There was either a fall or no change in the cardiac output and the intracardiac pressures did not alter following administration of the drug. The reaction to Digoxin in this type of patient with heart disease was in no way different from the response seen in two normal subjects included in the study but is in sharp contrast to the response elicited in patients in congestive heart failure.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Link

https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.4.3.366

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