A Developmental Complex Including Supravalvular Stenosis of the Aorta and Pulmonary Trunk

Author:

BLIEDEN LEONARD C.1,LUCAS RUSSELL V.1,CARTER JOHN B.1,MILLER KENNETH1,EDWARDS JESSE E.1

Affiliation:

1. From the Departments of Pediatrics and Pathology, University of Minnesota, Minneapolis and the Department of Pathology, United Hospitals-Miller Division, St. Paul, Minnesota.

Abstract

A developmental complex is described characterized by (1) supravalvular stenosis of the aorta and pulmonary trunk, (2) dysplasia of valves and (3) stenosis of ostia of coronary arteries and branches of the aortic arch. From the four cases described, it is evident that not all of the features of the complex need be present in a given case and, when present, some lesions are not of functional significance. The variations underly the potential for differences in the hemodynamic states of affected subjects.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

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