Affiliation:
1. From Western Reserve University, School of Medicine, Department of Physiology, Cleveland, Ohio.
Abstract
Sequential experimental studies are reviewed which, when properly integrated, confirm the concept that the responses of the ventricles, however measured, are determined by the initial length of fibers, provided that the functional state of the myocardium is not altered. Some of the established factors are discussed which may obscure the evidence that this basic law is of importance under normal and pathologic conditions.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine
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