The Postpericardiotomy Syndrome and Antiheart Antibodies

Author:

ENGLE MARY ALLEN1,MCCABE JOHN C.1,EBERT PAUL A.1,ZABRISKIE JOHN1

Affiliation:

1. From the Departments of Pediatrics and Surgery of the New York Hospital-Cornell University Medical Center, and from the Rockefeller University, New York, New York.

Abstract

In a prospective, double-blind study, heart-reactive antibody in high titer was detected, using an indirect immunofluorescent technique, in the serum of patients in whom the postpericardiotomy syndrome developed after intrapericardial surgery. The syndrome occurred in 26 of 86 consecutive longterm survivors of such surgery, an incidence of 30%. Presence of antibody correlated closely with the clinical syndrome. Demonstration of this antiheart antibody in high titer appears to offer laboratory confirmation of the syndrome.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference18 articles.

1. The postpericardiotomy syndrome

2. The postpericardiotomy and postperfusion syndromes;Heart Bull,1965

3. com.atypon.pdfplus.internal.model.plusxml.impl.AuthorGroup@4a88c539 : Postoperative syndromes. In Moss AJ ADAMS FH Heart Disease in Infants and Children. Baltimore The Williams and Wilkins Co. 1968 p 1087

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