Affiliation:
1. From the Cardiovascular Division of The Johns Hopkins University School of Medicine and The Johns Hopkins Hospital, Baltimore, Maryland.
Abstract
A total of 58 observations of simultaneous left ventricular pressure and apex-cardiograms (ACG) was made on 18 patients. An
a
wave percentage amplitude (aWPA) of greater than 15% of the total deflection of the ACG indicated an increase in left ventricular end-diastolic pressure (LVEDP). In 12 observations on six patients, an aWPA of less than 15% was associated with a high LVEDP. Patients with high LVEDP and aWPA of less than 15% had a high early left ventricular diastolic pressure with further rise in pressure prior to atrial contraction. These patients had small LV
a
waves ("atrial kick"). The aWPA of the ACG correlated better with the magnitude of the LV
a
wave than the absolute level of LVEDP in all patients. Correlation was good between changes in aWPA and changes in LVEDP in individual patients; but the ACG as an indirect means of evaluating left ventricular function is limited by the fact that elevations in LVEDP can exist in the presence of a normal aWPA. The ACG is a complex tracing reflecting not only intracardiac pressures, but changes in left ventricular volume, compliance, position, and perhaps left atrial function as well.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine
Cited by
53 articles.
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