The Dye Dilution Method for Describing the Central Circulation

Author:

NEWMAN ELLIOT V.1,MERRELL MARGARET1,GENECIN ABRAHAM1,MONGE CARLOS1,MILNOR WILLIAM R.1,MCKEEVER WILLIAM P.1

Affiliation:

1. From the Department of Medicine of the Johns Hopkins University School of Medicine and Hospital and the Department of Biostatistics of the School of Hygiene and Public Health (Paper No. 269), Baltimore, Md.

Abstract

In addition to providing accurate measurement of circulation times and cardiac output, the dye dilution curves may reveal the size and location of the volumes of blood with which the dye is mixed in the central circulatory system. A trivalent approach to the analysis of these curves is presented by a combination of theoretic analysis, mechanical system experimentation and clinical observation.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference8 articles.

1. The pulmonary circulation time, the quantity of blood in the Iungs and the output of the heart;STEWART G. N.;Am. J. Phvsiol.,1921

2. Studies on the circulation. I. Injection method: Physical and mathematical considerations;STEWART G. N.;Am. J. Physiol.,1929

3. Studies on circulation. IV. Further analysis of the injection method and of changes in hemnodynamics under physiological and pathological conditions;MOORE J. W.;Am. J. Physiol.

4. Theory of the measurement of blood flow by the dilution of an indicator

5. 8MILNOR W. R. TALBOT S. A. 11cKEEVER WV. P. MARYE R. B. AND NEWMAN E. V.: A photoelectric "ear densimeter" for continuous recording of arterial dye concentration in the determination of cardiac output by the dye dilution method. In preparation.

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