Affiliation:
1. From the Departments of Pathology of United Hospitals-Miller Division, St. Paul, Minnesota, and the University of Minnesota, Minneapolis, Minnesota.
Abstract
A review of 55 specimens with congenital heart disease from subjects with Down's syndrome (Mongolism) showed a variety of malformations. For each case a major anomaly was identified and, when present, additional anomalies were recorded.
The three leading types of major anomalies, in order of decreasing frequency, were (1) persistent common atrioventricular canal (60%), isolated ventricular septal defect (29%), and tetralogy of Fallot either alone or in association with persistent common atrioventricular canal (14.5%).
Of the additional anomalies, the most common took the form either of an atrial septal defect at the fossa ovalis (50%) or patent ductus arteriosus (47%).
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine
Reference6 articles.
1. CONGENITAL CARDIAC MALFORMATIONS IN MONGOLISM
2. Cardiac malformation in mongolism;Amer J Med,1961
3. On the association of cardiac malformations with other congenital defects;St Barth Hosp Rep (London),1894
4. New accessions in cardiac anomalies: Pulmonary atresia of inflammatory origin; persistent ostium primum with Mongolian idiocy;Internat A M Museums Bull,1924
5. Pathologic study of persistent common atrioventricular canal
Cited by
66 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献