Affiliation:
1. From the Departments of Pathology of the Charles T. Miller Hospital, St. Paul, Minnesota, and of the University of Minnesota, Minneapolis, Minnesota.
Abstract
Among the wide variety of causes of angina pectoris, two major categories may be recognized: the anatomic, causing arterial obstruction, and the functional.
The anatomic causes may be divided according to anatomic sites as follows: (1) the major coronary arterial trunks and their epicardial branches, (2) the coronary ostia at the aorta, and (3) the intramyocardial "small" arteries. The major coronary arteries are by far the most common sites for anatomic lesions. Atherosclerosis in its various anatomic manifestations is responsible for about 90% of the cases of angina. Commonly, hypertension and, less commonly, valvular disease are associated. The balance of cases of angina result from various states given below. Nonatheromatous diseases of the major coronary arteries include embolism, primary dissecting aneurysm of a coronary artery, arteritis, and anomalous communication of a coronary artery. Coronary ostial narrowing results from various diseases of the aorta including atherosclerosis, saccular and dissecting aneurysm, inflammation, and calcification of the aorta in relation to origin of a coronary artery. Lesions causing obstruction of the intramyocardial arteries are commonly part of systemic diseases such as hematologic, embolic, metabolic, and degenerative.
Functional causes of angina pectoris include aortic valvular disease and functionally related conditions, thyroid disease, and pulmonary hypertension.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine
Reference49 articles.
1. Capillary rupture with intimal hemorrhage as a causative factor in coronary thrombosis;Arch Path (Chicago),1938
2. Thrombosis of the aorta and coronary arteries: With special reference to the "fibrinoid" lesions;Arch Path (Chicago),1936
3. Some factors in the causation of intimal haemorrhages and in the precipitation of coronary thrombi;Canad Med Ass J,1941
4. com.atypon.pdfplus.internal.model.plusxml.impl.AuthorGroup@2d4734fb
: Pathological physiology of Angina Pectoris and Acute Myocardial Infarction ed 2. New York American Heart Association Monograph 1968
5. Incidence and localization of coronary artery occlusions;Arch Path (Chicago),1941
Cited by
17 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Pain in Mucopolysaccharidoses: Analysis of the Problem and Possible Treatments;International Journal of Molecular Sciences;2018-10-08
2. Doehle-Heller aortitis: speed of decision is what saves life;Asian Cardiovascular and Thoracic Annals;2012-08
3. Nonatherosclerotic Ischemic Heart Disease;Coronary Heart Disease;2011-12-06
4. Syphilitic aortitis;Catheterization and Cardiovascular Interventions;2001
5. Clinical Subsets;Textbook of Angiology;2000