Affiliation:
1. From the Departments of Medicine (Cardiology Division), Public Health-Epidemiology, and Biostatisics, University of Alabama Medical Center, Birmingham, Alabama.
Abstract
To examine the electrocardiographic response to exercise in an older population, 280 participants in a longitudinal study of cerebrovascular disease were tested. Subjects were randomly selected from the total 50 to 69-year-old population of Birmingham, Alabama. Approximately 60% of the participants reached a heart rate more than 80% of their predicted maximal heart rate.
Subjects were divided into three groups on clinical grounds: (I) vascular disease, (II) risk factor(s) only, and (III) normal. Positive tests (at least 0.10 mv of ischemic ST-segment depression) were most frequent in group I (24%), though not significantly different from group II (19%) and group III (12%).
Hypercholesterolemia was significantly associated with a positive exercise test only in those subjects with vascular disease. Nonspecific ST-T wave changes on the resting electrocardiogram were associated with a positive test in all subjects, but with only a borderline test in those subjects without vascular disease. No significant associations were noted between abnormal exercise test and either cigarette smoking or hypertension.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine
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