1. From the Department of Medicine (H.L.N., J.M.G., G.R., F.A.S.), Division of Cardiovascular Medicine, the Department of Medicine (J.S.S.), Division of Geriatric Medicine, and the Department of Quantitative Health Sciences (J.S.S., J.Y., R.J.G.), University of Massachusetts Medical School, Worcester, Mass; and the Thrombosis and Atherosclerosis Research Institute (F.A.S.), McMaster University–Faculty of Health Sciences, Hamilton, Ontario, Canada.