Worldwide Survey of COVID-19–Associated Arrhythmias-Reference-Cited by-同舟云学术

Worldwide Survey of COVID-19–Associated Arrhythmias

Published:2021-03 Issue:3 Volume:14 Page:
ISSN:1941-3149
Container-title:Circulation: Arrhythmia and Electrophysiology
language:en
Short-container-title:Circ: Arrhythmia and Electrophysiology

Author:

Coromilas Ellie J.¹^ORCID,Kochav Stephanie¹,Goldenthal Isaac¹^ORCID,Biviano Angelo¹^ORCID,Garan Hasan¹,Goldbarg Seth²^ORCID,Kim Joon-Hyuk²,Yeo Ilhwan²,Tracy Cynthia³,Ayanian Shant³,Akar Joseph⁴^ORCID,Singh Avinainder⁴^ORCID,Jain Shashank⁴^ORCID,Zimerman Leandro⁵^ORCID,Pimentel Maurício⁵^ORCID,Osswald Stefan⁶^ORCID,Twerenbold Raphael⁶^ORCID,Schaerli Nicolas⁶^ORCID,Crotti Lia⁷⁸^ORCID,Fabbri Daniele⁷⁸,Parati Gianfranco⁷⁸^ORCID,Li Yi⁹^ORCID,Atienza Felipe¹⁰¹¹^ORCID,Zatarain Eduardo¹⁰¹¹^ORCID,Tse Gary¹²¹³¹⁴^ORCID,Leung Keith Sai Kit¹⁵^ORCID,Guevara-Valdivia Milton E.¹⁶^ORCID,Rivera-Santiago Carlos A.¹⁶^ORCID,Soejima Kyoko¹⁷,De Filippo Paolo¹⁸^ORCID,Ferrari Paola¹⁸^ORCID,Malanchini Giovanni¹⁸^ORCID,Kanagaratnam Prapa¹⁹^ORCID,Khawaja Saud¹⁹,Mikhail Ghada W.¹⁹,Scanavacca Mauricio²⁰^ORCID,Abrahão Hajjar Ludhmila²⁰,Rizerio Brenno²⁰^ORCID,Sacilotto Luciana²⁰^ORCID,Mollazadeh Reza²¹^ORCID,Eslami Masoud²¹,Laleh far Vahideh²¹^ORCID,Mattioli Anna Vittoria²²^ORCID,Boriani Giuseppe²²^ORCID,Migliore Federico²³^ORCID,Cipriani Alberto²³^ORCID,Donato Filippo²³^ORCID,Compagnucci Paolo²⁴^ORCID,Casella Michela²⁴^ORCID,Dello Russo Antonio²⁴,Coromilas James²⁵^ORCID,Aboyme Andrew²⁵^ORCID,O’Brien Connor Galen²⁶^ORCID,Rodriguez Fatima²⁷^ORCID,Wang Paul J.²⁷^ORCID,Naniwadekar Aditi²⁸^ORCID,Moey Melissa²⁸^ORCID,Kow Chia Siang²⁹,Cheah Wee Kooi³⁰,Auricchio Angelo³¹^ORCID,Conte Giulio³¹^ORCID,Hwang Jongmin³²^ORCID,Han Seongwook³²,Lazzerini Pietro Enea³³³⁴^ORCID,Franchi Federico³³³⁴^ORCID,Santoro Amato³³³⁴^ORCID,Capecchi Pier Leopoldo³³³⁴^ORCID,Joglar Jose A.³⁵^ORCID,Rosenblatt Anna G.³⁵^ORCID,Zardini Marco³⁶^ORCID,Bricoli Serena³⁶^ORCID,Bonura Rosario³⁶^ORCID,Echarte-Morales Julio³⁷,Benito-González Tomás³⁷^ORCID,Minguito-Carazo Carlos³⁷^ORCID,Fernández-Vázquez Felipe³⁷^ORCID,Wan Elaine Y.¹^ORCID

Affiliation:

1. Department of Medicine, Division of Cardiology, Columbia University Vagelos College of Physicians & Surgeons (E.J.C., S. Kochav, I.G., A.B., H.G., E.Y.W.).

2. New York Presbyterian Queens, Weill Medical College (S.G., J.-H.K., I.Y.).

3. The George Washington University School of Medicine & Health Sciences, The GW Medical Faculty Associates, Washington, DC (C.T., S.A.).

4. Section of Cardiovascular Disease, Yale University School of Medicine, New Haven, CT (J.A., A. Singh, S.J.).

5. Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Brazil (L.Z., M.P.).

6. Department of Cardiology & Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, University of Basel, Switzerland (S.O., R.T., N.S.).

7. Istituto Auxologico Italiano, IRCCS, Department of Cardiovascular, Neural & Metabolic Sciences, San Luca Hospital, Milan, Italy (L.C., D.F., G.P.).

8. Department of Medicine & Surgery, University of Milano-Bicocca, Milan, Italy (L.C., D.F., G.P.).

9. Wuhan Asia General Hospital, China (Y.L.).

10. Department of Cardiology, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM) (F.A., E.Z.).

11. CIBERCV, Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares, Instituto de Salud Carlos III, Madrid, Spain (F.A., E.Z.).

12. Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, China (G.T.).

13. School of Life Sciences. The Hospital Authority of Hong Kong, Hong Kong, China (G.T.).

14. Laboratory of Cardiovascular Physiology, Li Ka Shing Institute of Health Sciences, Hong Kong, China (G.T.).

15. Aston Medical School, Aston University, Birmingham, United Kingdom (K.C.K.L.).

16. UMAE Hospital de Especialidades Dr. Antonio Fraga Mouret CMN La Raza IMSS, CDMX, Mexico (M.E.G.-V., C.A.R.-S.).

17. Kyorin University School of Medicine, Tokyo, Japan (K.S.).

18. Electrophysiology & Cardiac Pacing Unit, Cardiology Department, ASST Papa Giovanni XXIII, Bergamo, Italy (P.D.F., P.F., G.M.).

19. Imperial College Healthcare NHS Trust, London, United Kingdom (P.K., S. Khawaja, G.W.M.).

20. Heart Institute (InCor), Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, Brazil (M.S., A.H., B.R., L.S.).

21. Department of Cardiology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Iran (R.M., M.E., V.L.f.).

22. University of Modena & Reggio Emilia, Modena, Italy (V.M., G.B.).

23. Department of Cardiac, Thoracic, Vascular Sciences & Public Health, University of Padova, Italy (F.M., A.C., F.D.).

24. Cardiology & Arrhythmology Clinic, University Hospital “Ospedali Riuniti,” Marche Polytechnic University, Ancona, Italy (P.C., M.C., A.D.R.).

25. Division of Cardiovascular Disease & Hypertension, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ (J.C., A. Aboyme).

26. Department of Medicine, Division of Cardiology, University of California San Francisco School of Medicine (C.G.O.).

27. Division of Cardiology, Stanford University, CA (F.R., P.J.W.).

28. East Carolina University, Greenville, NC (A.N., M.M.).

29. School of Postgraduate Studies, International Medical University, Kuala Lumpur (C.S.K.).

30. Department of Medicine & Clinical Research Center, Taiping Hospital, Perak, Malaysia (W.K.C.).

31. Division of Cardiology, Fondazione Cardiocentro Ticino, Lugano, Switzerland (A. Auricchio, G.C.).

32. Division of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Hospital, Daegu, South Korea (J.H., S.H.).

33. Department of Medical Sciences, Surgery & Neurosciences, University of Siena, Italy (P.E.L., F.F., A. Santoro, P.L.C.).

34. Azienda Ospedaliera Universitaria Senese (AOUS), Siena, Italy (P.E.L., F.F., A. Santoro, P.L.C.).

35. University of Texas Southwestern Medical Center, Dallas (J.A.G., A.G.R.).

36. Division of Cardiology, University Hospital “Ospedale Maggiore,” Parma, Italy (M.Z., S.B., R.B.).

37. Department of Cardiology, University Hospital of Leon, Spain (J.E.-M., T.B.-G., C.M.-C., F.F.-V.).

Abstract

Background: Coronavirus disease 2019 (COVID-19) has led to over 1 million deaths worldwide and has been associated with cardiac complications including cardiac arrhythmias. The incidence and pathophysiology of these manifestations remain elusive. In this worldwide survey of patients hospitalized with COVID-19 who developed cardiac arrhythmias, we describe clinical characteristics associated with various arrhythmias, as well as global differences in modulations of routine electrophysiology practice during the pandemic. Methods: We conducted a retrospective analysis of patients hospitalized with COVID-19 infection worldwide with and without incident cardiac arrhythmias. Patients with documented atrial fibrillation, atrial flutter, supraventricular tachycardia, nonsustained or sustained ventricular tachycardia, ventricular fibrillation, atrioventricular block, or marked sinus bradycardia (heart rate<40 bpm) were classified as having arrhythmia. Deidentified data was provided by each institution and analyzed. Results: Data were collected for 4526 patients across 4 continents and 12 countries, 827 of whom had an arrhythmia. Cardiac comorbidities were common in patients with arrhythmia: 69% had hypertension, 42% diabetes, 30% had heart failure, and 24% had coronary artery disease. Most had no prior history of arrhythmia. Of those who did develop an arrhythmia, the majority (81.8%) developed atrial arrhythmias, 20.7% developed ventricular arrhythmias, and 22.6% had bradyarrhythmia. Regional differences suggested a lower incidence of atrial fibrillation in Asia compared with other continents (34% versus 63%). Most patients in North America and Europe received hydroxychloroquine, although the frequency of hydroxychloroquine therapy was constant across arrhythmia types. Forty-three percent of patients who developed arrhythmia were mechanically ventilated and 51% survived to hospital discharge. Many institutions reported drastic decreases in electrophysiology procedures performed. Conclusions: Cardiac arrhythmias are common and associated with high morbidity and mortality among patients hospitalized with COVID-19 infection. There were significant regional variations in the types of arrhythmias and treatment approaches.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference32 articles.

1. World Health Organization. Coronavirus Disease (COVID-19) Weekly Epidemiological Update - Nov 10 2020. Published November 10 2020. Accessed November 11 2020. https://www.who.int/publications/m/item/weekly-epidemiological-update---10-november-2020

2. Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the COVID-19 Pandemic

3. Guidance for cardiac electrophysiology during the COVID-19 pandemic from the Heart Rhythm Society COVID-19 Task Force; Electrophysiology Section of the American College of Cardiology; and the Electrocardiography and Arrhythmias Committee of the Council on Clinical Cardiology, American Heart Association.;Lakkireddy DR;Heart Rhythm,2020

4. Cardiac Arrhythmias in COVID-19 Infection

5. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China

Cited by 143 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Outcomes of Covid-19 among patients with ischemic heart disease: A propensity matched analysis;Heart & Lung;2024-11

2. Atrial lead system for enhanced P-wave recording: A comparative study on optimal leads using gradient boosting and deep learning algorithms;Biomedical Signal Processing and Control;2024-11

3. Inpatient mortality and outcomes of COVID-19 among patients with non-ischemic cardiomyopathy: A propensity matched analysis;Heart & Lung;2024-11

4. Nationwide Trends in Hospitalizations for Atrial Fibrillation and Flutter in the United States before and during the Outbreak of the COVID-19 Pandemic;Journal of Clinical Medicine;2024-08-19

5. Increased interleukin‐6 levels are associated with atrioventricular conduction delay in severe COVID‐19 patients;Journal of Arrhythmia;2024-07-31