1. From the Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis (H.M., D.P.Z., S.T.M., J.W.); Department of Cardiovascular Therapeutics/Cardiovascular Medicine, Okayama University Graduate School of Medicine, Okayama, Japan (H.M., S.T.M.); and Department of Pharmaceutical Sciences, College of Pharmacy, Northeast Ohio Medical University, Rootstown (J.W.).