1. From the Department of Medicine (A.F.B.), Heart and Vascular Institute (A.A.H., W.I.S., M.B., K.T., M.K., W.J., L.L.R., R.G., B.D.L., O.M.W.), Cerebrovascular Center (M.S.H., A.R., K.U., D.W., P.R., M.B.), and Digestive Disease Institute (J.V., G.Z., D.G.), Cleveland Clinic Foundation, Cleveland, OH.