1. From the Division of Cardiology (A.L.A.), Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland; Department of Internal Medicine (A.L.A., O.A., T.K.), Päijät-Häme Central Hospital, Lahti, Finland; Institute of Clinical Medicine (J.T.T., M.J.J., H.V.H.), Department of Internal Medicine, University of Oulu, Oulu, Finland; and National Institute for Health & Welfare (H.A.R., A.R.), Helsinki, Finland.