Overexpression of IL-18 Decreases Intimal Collagen Content and Promotes a Vulnerable Plaque Phenotype in Apolipoprotein-E

Overexpression of IL-18 Decreases Intimal Collagen Content and Promotes a Vulnerable Plaque Phenotype in Apolipoprotein-E–Deficient Mice

Published:2004-12 Issue:12 Volume:24 Page:2313-2319
ISSN:1079-5642
Container-title:Arteriosclerosis, Thrombosis, and Vascular Biology
language:en
Short-container-title:ATVB

Author:

de Nooijer R.¹,von der Thüsen J.H.¹,Verkleij C.J.N.¹,Kuiper J.¹,Jukema J.W.¹,van der Wall E.E.¹,van Berkel Th.J.C.¹,Biessen E.A.L.¹

Affiliation:

1. From the Division of Biopharmaceutics (R.d.N., J.H.v.d.T., C.J.N.V., J.K., Th.J.C.v.B., E.A.L.B.) and the Department of Cardiology (R.d.N., J.W.J., E.E.v.d.W.), Leiden University Medical Center, Leiden, the Netherlands.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine

Reference40 articles.

1. Atherosclerosis — An Inflammatory Disease

2. IFN-gamma potentiates atherosclerosis in ApoE knock-out mice.

3. Exogenous Interferon-γ Enhances Atherosclerosis in Apolipoprotein E−/− Mice

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