1. From the Departments of Pathology and Laboratory Medicine & Cellular and Molecular Medicine (S.C.W.), University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Gill Heart Institute (D.L.R., A.D.), Division of Cardiovascular Medicine, University of Kentucky, Lexington; Amgen (S.J.S.), Thousand Oaks, Calif; and Washington University School of Medicine (W.Y.), Division of Rheumatology, St. Louis, Mo.