1. From the Departments of Medicine (C.y.Y., J.L.R., H.-H.C., C.-H.C., Y.A., H.J.P., A.A.T.) and Biochemistry (C.y.Y.), Baylor College of Medicine, Houston, Tex, and Center for Developmental Pharmacology and Toxicology (C.V.S.), Children’s Research Institute, Ohio State University, Columbus, Ohio.