1. From the Department of Vascular Medicine (J.R., M.C.N., J.J.P.K., E.S.G.S., J.A.K.), Academic Medical Center, University of Amsterdam, the Netherlands; Leiden University Medical Center (J.W.J.), Department of Cardiology, Leiden, The Netherlands; and the Center for Molecular Medicine and Therapeutics (C.J.R., M.R.H.), University of British Columbia, Vancouver, British Columbia, Canada