1. From the Department of Metabolism, Endocrinology, and Molecular Medicine (H.K., T.S., H.Y., K. Motoyama, K. Mori, S.F., M.E., T.S., Y.N.), Osaka City University Graduate School of Medicine, Osaka, Japan; Daiichi Fine Chemical Co Ltd (H.T., H.M.), Takaoka, Japan; and the Department of Biochemistry and Molecular Vascular Biology (S.S., Y.Y., H.Y., T.W., H.Y.), Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.