The Clinical Effect of Dihydroergocornine Methanesulphonate (DHO-180) in Arterial Hypertension: A Preliminary Report-Reference-Cited by-同舟云学术

The Clinical Effect of Dihydroergocornine Methanesulphonate (DHO-180) in Arterial Hypertension: A Preliminary Report

Published:1950-04 Issue:4 Volume:1 Page:686-691
ISSN:0009-7322
Container-title:Circulation
language:en
Short-container-title:Circulation

Author:

TANDOWSKY R. M.¹

Affiliation:

1. From the Department of Internal Medicine, College of Medical Evangelists and the Medical Wards of the Los Angeles General Hospital.

Abstract

A controlled clinical and statistical study of 47 unselected patients with sustained arterial hypertension who received dihydroergocornine intravenously and orally is presented. The study demonstrates the central effect of this drug in temporarily lowering the systolic and diastolic blood pressure and pulse rate. This action occurs irrespective of associated pathology or extent of the hypertensive state when the drug is given parenterally. Orally, little effect was demonstrated.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Link

https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.1.4.686

Reference11 articles.

1. Studies on hypertension; Effect on renal function of decreasing blood pressure of patients with hypertension;GREGORY R.;Texas Rep. Biol. & Med.,1943

2. 2BLUNTSCHLI H. J.: The hypotensive effect of an ergot derivative dihydroergocornine. Helvet. med. acta. 15: 417 1948.

3. : tiber die blutdrucksenkende Wirkung eines Ergot-Derivatives "Dihydroergocornin" bei Hypertension. Helvet. med. acta 15: Fasc. 4/5 1948.

4. The effect of ergot derivatives on the circulation in man with special reference to two new hydrogenated compounds (dihydroergotamine and dihydroergocornine)

5. LVergobosine, un nouvel alcaloide de l'ergot de seigle, soluble dans leau. Compt. rend;STOLL A.;Acad. Sc.,1935

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