Significance of the Pulmonary Vascular Bed in Congenital Heart Disease

Author:

FERENCZ CHARLOTTE1,DAMMANN J. FRANCIS1

Affiliation:

1. From the Department of Pediatrics of the Johns Hopkins University and the Cardiac Clinic, Harriet Lane Home, Johns Hopkins Hospital, Baltimore, Md., and the Department of Surgery, University of Virginia, Charlottesville, Va.

Abstract

A microscopic study was made of the lungs of 18 patients with congenital malformations of the heart in which there was obstruction of pulmonary venous drainage. Alterations in various components of the pulmonary vascular bed and of the lung parenchyma were described and correlated with the clinical course and the type of malformation present. A quantitative evaluation of the pulmonary arterial thickening was made by determining the lumen:wall ratio of small vessels. The anatomic alterations found in these children were compared to those of adults with acquired mitral stenosis.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference19 articles.

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3. Valvotomy for Mitral Stenosis

4. THE SMALL PULMONARY VESSELS IN MITRAL STENOSIS

5. The clinicopathologic correlation of lung biopsies in mitral stenosis

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