1. From the Department of Neurological and Psychiatric Sciences (M.L., G.P., A.M.B., G.T., P.V., D.I.), University of Florence, Florence, Italy; the National Research Council of Italy (CNR-CSFET) (A.D.C.), Italian Longitudinal Study on Aging, Florence, Italy; Health Area 10 (S.S., M.C.B., G.L., A.G.), Florence, Italy; and the Department of Public Health Sciences (C.D.A.W.), The Guy’s, Kings College, and St Thomas’ Hospital Medical and Dental School, Guy’s Campus, London, England.