Cerebrospinal fluid lactate dehydrogenase levels in early stroke and transient ischemic attacks.

Author:

Lampl Y1,Paniri Y1,Eshel Y1,Sarova-Pinhas I1

Affiliation:

1. Department of Neurology, Edith Wolfson Medical Center, Holon, Israel.

Abstract

We examined the concentrations of lactate dehydrogenase in the cerebrospinal fluid of 25 patients with strokes and 15 patients with transient ischemic attacks less than or equal to 8 hours after the onset of the vascular event and in a control group of 21 patients. We found significantly higher concentrations in the stroke patients (40.9 +/- 14.5 units/l) than in the transient ischemic attack patients (11.8 +/- 2.9 units/l, p less than 0.001) and the controls (11.2 +/- 6.7 units/l, p less than 0.001). Among the stroke patients, we found a significantly higher lactate dehydrogenase concentration in those with cortical strokes (n = 12, 50 +/- 12.3 units/l) than in those with lacunar white matter infarcts (n = 5, 26.4 +/- 6.5 units/l; p less than 0.001) and those with basal ganglia infarcts (n = 8, 36.37 +/- 11.7 units/l; p less than 0.05). Our study offers a supplementary examination for diagnosing cortical or subcortical infarction during the early stage of the event, with the possibility of distinguishing precisely stroke from transient ischemic attack during the first hours after onset of the event.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Advanced and Specialized Nursing,Cardiology and Cardiovascular Medicine,Neurology (clinical)

Reference22 articles.

1. The Clinical Implications of Spinal-Fluid Lactic Dehydrogenase Activity

2. Bedl HK Bomb BS Bedi T Shanna V: Serum and cerebrospinal fluid lactic dehydrogenase in cerebrovascular disease. / Assoc Physicians India 1974;12:900-905

3. Lactic dehydrogenase in the cerebrospinal fluid in patients with cerebral stroke;Gdakowics B;Neurol NeurochirPol,1971

4. Glutamic Oxalacetic Transaminase in Serum and Cerebrospinal Fluid of Patients with Cerebrovascular Accidents

5. Cerebrospinal-Fluid Transaminase Concentrations in Clinical Cerebral Infarctions

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