1. From the Julius Centre for Patient Oriented Research (J.M.K., M.A.A.J.v.d.B., Y.v.d.G., A.A.) and the Department of Neurology (A.A.), University Medical Centre Utrecht, Utrecht, the Netherlands, and the Department of Haematology (B.C.T.), Department of Neurology (E.E.L.M.B.), Department of Obstetrics, Gynecology and Reproductive Medicine (F.M.H.), and the Department of Clinical Epidemiology (F.R.R.), Leiden University Medical Centre, Leiden, the Netherlands.