Affiliation:
1. From the Departments of Neurology (J.G.H., C.S., C.J.G.L, B.N.) and Neuroradiology (B.T.), University of Erlangen-Nuremberg, Germany; the Smell & Taste Clinic (T.H.), and the Department of Otorhinolaryngology, University of Dresden Medical School, Germany.
Abstract
Background and Purpose—
The aim of the study was to assess whether and how frequently patients with acute first-ever stroke exhibit gustatory dysfunction.
Methods—
We performed a 1-year prospective observational study. Gustatory function was assessed using the standardized “taste strips” test. In addition, we assessed olfactory function, swallowing, stroke location, comorbidities, and the patients’ medication.
Results—
A total of 102 consecutive patients were enrolled (45 female, 57 male; mean age, 63 years); 31 of them (30%) exhibited gustatory loss and 7 (6%) had lateralized impairment of taste function. Predictors of impaired taste function were male gender (
P
=0.003), high National Institutes of Health Stroke Scale (NIHSS) score at admission (
P
=0.009), coexisting swallowing dysfunction (
P
=0.026), and a stroke of partial anterior circulation subtype (PACS) (
P
=0.008). In particular, in hypogeusic patients the lesion was most frequently localized in the frontal lobe (
P
=0.009). Follow-up examinations in 14 patients indicated improvement of taste sensitivity.
Conclusion—
Taste disorders after stroke are frequent. A significant association was found for male gender, high NIHSS score, swallowing disorder, and PACS, particularly in the frontal lobe. Generally, taste disorders after stroke seem to have a good prognosis.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Advanced and Specialised Nursing,Cardiology and Cardiovascular Medicine,Clinical Neurology
Cited by
76 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献